Episode Overview
Derek and Addison's relationship faces a serious challenge when an old acquaintance arrives at Seattle Grace, bringing upheaval for several staff members. Burke and Cristina find their bond strained when one of her secrets is revealed. Meanwhile, Alex and Izzie are both reminded of their own hidden truths during the Code Black event. A brash new doctor arrives, much to Derek’s irritation. One patient experiences uncontrollable orgasms, leading to some intriguing discussions among the team. George is on a quest to show Meredith that he's more than just her roommate. Additionally, Derek treats a patient with a rare condition who needs familial support. Inspired by one of his patients, Burke decides to have a candid conversation with Meredith and Cristina about following through on their commitments. Lastly, Meredith uncovers more about her family history, revealing details she might have preferred to stay hidden.